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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 541291Generated: October 27, 2026

tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate → Tert-butyl 4-(4-bromophenyl)-4-hydroxy-2-methylpiperidine-1-carboxylate

https://huagongshe.com/reaction/541291

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2-methyl-4-oxopiperidine-1-carboxylateHCID 12992764—
Reactant1-Boc-4-(4-bromo-phenyl)-piperidin-4-olHCID 18379557—
ProductTert-butyl 4-(4-bromophenyl)-4-hydroxy-2-methylpiperidine-1-carboxylateHCID 70907770—

Reaction Steps

The title compound was synthesized using a procedure similar to that used for the preparation of compound 1.1 and using tert-butyl 2-methyl-4-oxopiperidine-1-carboxylate in place of tert-butyl 4-oxopiperidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08871790B2
Source datasetuspto-grants-2014_10
ORD IDord-7b331fe34c9e4ea798a677a56944ce5f
Source noteuspto-grants-2014_10