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HRID 541393作成日：2026年10月25日

Methyl 5-cyano-4-cyclobutyl-2-methylbenzoate → Methyl 5-carbamimidoyl-4-cyclobutyl-2-methylbenzoate hydrochloride

https://huagongshe.com/reaction/541393

反応式

関与物質

役割名称HCID仕込み量
反応物Methyl 5-cyano-4-cyclobutyl-2-methylbenzoateHCID 68288299—
反応物Methyl 5-carbamimidoyl-2,4-dimethylbenzoate hydrochlorideHCID 68288602—
反応物Methyl 5-cyano-2,4-dimethylbenzoateHCID 68288737—
反応物Methyl 5-(N'-hydroxycarbamimidoyl)-2,4-dimethylbenzoateHCID 86672521—
生成物Methyl 5-carbamimidoyl-4-cyclobutyl-2-methylbenzoate hydrochlorideHCID 68288852—

反応手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for preparation of methyl 5-(N′-hydroxycarbamimidoyl)-2,4-dimethylbenzoate (compound 2.4) and methyl 5-carbamimidoyl-2,4-dimethylbenzoate hydrochloride (compound 2.5) using methyl 5-cyano-4-cyclobutyl-2-methylbenzoate (compound 152.4) instead of methyl 5-cyano-2,4-dimethylbenzoate (compound 2.3).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08871790B2
出典データセットuspto-grants-2014_10
ORD IDord-803fc1f6de85457ea9a27b3d0460b5e0
出典メモuspto-grants-2014_10