HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,4-dichloropyrimidine → tert-Butyl [3-(2-{3-[(5-bromo-2-chloropyrimidin-4-yl)amino]phenyl}ethyl)phenyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,4-dichloropyrimidine | HCID 289973 | — |
| Reactant | tert-Butyl {3-[2-(3-aminophenyl)ethyl]phenyl}carbamate | HCID 57962516 | — |
| Product | tert-Butyl [3-(2-{3-[(5-bromo-2-chloropyrimidin-4-yl)amino]phenyl}ethyl)phenyl]carbamate | HCID 57962319 | 70% |
Reaction Steps
This compound was prepared according to the procedure of Example B5, step G using 5-bromo-2,4-dichloropyrimidine and tert-butyl {3-[2-(3-aminophenyl)ethyl]phenyl}carbamate as the starting materials in 70% yield. LCMS calculated for C23H25BrClN4O2 (M+H)+: m/z=503.1, 505.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-556e2647bd9b4a50913b8fd9f0dbd523 |
| Source note | uspto-grants-2014_10 |