HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-iodo-4-nitrobenzoate → Methyl 2-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-4-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-iodo-4-nitrobenzoate | HCID 232745 | — |
| Reactant | tert-Butyl 3-ethynylphenylcarbamate | HCID 11275982 | — |
| Product | Methyl 2-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-4-nitrobenzoate | HCID 57961859 | 87% |
Reaction Steps
This compound was prepared according to the procedure of Example B19 step C, using tert-butyl (3-ethynylphenyl)carbamate and methyl 2-iodo-4-nitrobenzoate as the starting materials in 87% yield. LCMS calculated for C21H21N2O6(M+H)+: m/z=397.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871753B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-6f507852724743249a63560f1d1103b7 |
| Source note | uspto-grants-2014_10 |