HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 13882890, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Methyl-4-nitrophenol | HCID 17412 | — |
| Reactant | 4-Chloro-2,6-bis-trifluoromethyl-nicotinic acid ethyl ester | HCID 13882877 | — |
| Solvent | Methyl Isobutyl Ketone | HCID 7909 | — |
| Product | HCID 13882890 | HCID 13882890 | 95.2% |
Reaction Steps
This product was prepared as described in Example 31: 7.0 g (0.022 mol) of product of Example 19, 3.31 g (0.024 mol) of K2CO3, 3.33 g (0.022 mol) of 3-methyl-4-nitrophenol in 75 ml of methyl isobutyl ketone were reacted affording 9.18 g of an oil. Purification by HPLC using 5% ethyl acetate/cyclohexane as eluting solvent gave 5.31 g (55.1%) of product as a yellow solid; mp 55°-57° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04655816 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-df08ab1f36c547788cdbb118c541d977 |
| Source note | uspto-grants-1987_04 |