HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → Ethyl 2,6-bis(trifluoromethyl)-4-acetoxy-5-methyl-3-pyridinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 178469144 | HCID 178469144 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Ethyl 2,6-bis(trifluoromethyl)-4-acetoxy-5-methyl-3-pyridinecarboxylate | HCID 13882902 | 95% |
Reaction Steps
A mixture of 1.26 g (0.016 mol) of pyridine, 1.61 g (0.016 mol) of acetic anhydride and 5.0 g (0.016 mol) of product of Example 35 in 50 ml of ether was stirred for 3 hours and filtered. The filtrate was concentrated in vacuo to give 5.38 g (95%) of product as a solid; mp 49°-51° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04655816 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-c64b702a90224576b8e5855e0fe5f394 |
| Source note | uspto-grants-1987_04 |