Hydroxyamine hydrochloride → 2-methoxy-6-(N,N-diethylsulfamoyl)-1-naphthaldoxime

HRID 542161Notes

Reaction equation

HRID 542161 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([S:12](=[O:19])(=[O:18])[N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])[CH:8]=2)[C:3]=1[CH:20]=O.Cl.[NH2:23][OH:24].[C:25]([O-])(=O)C.[Na+]>>[CH3:25][O:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([S:12](=[O:18])(=[O:19])[N:13]([CH2:14][CH3:15])[CH2:16][CH3:17])[CH:8]=2)[C:3]=1[CH:20]=[N:23][OH:24]

Participants

4

Reactant 3

HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium AcetateHCID 202094342-hydroxy-6-(N,N-diethylsulfamoyl)-1-naphthaldehyde

Product 1

HCID 736657072-methoxy-6-(N,N-diethylsulfamoyl)-1-naphthaldoxime

Procedure

The 2-hydroxy-6-(N,N-diethylsulfamoyl)-1-naphthaldehyde thus-obtained was methylated and then reacted using hydroxylamine hydrochloride and sodium acetate in the same manner as described in Synthesis Example 2 to obtain 2-methoxy-6-(N,N-diethylsulfamoyl)-1-naphthaldoxime.

Workup

  1. customreacted
  2. customas described in Synthesis Example 2

Sources & evidence

ORD record
ord-d5d2858d3e55423390e24e24529725c9
Source dataset
uspto-grants-1987_04
Patent number
US04656126

Reaction notes

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