HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → HCID 20209483, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(4,4-Bis(4-fluorophenyl)butyl)piperazine | HCID 79729 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 20209483 | HCID 20209483 | — |
Reaction Steps
To a solution of 3.3 g (0.01 mole) of 1-[4,4-bis(p-fluorophenyl)butyl]piperazine in 10 ml of CHCl3 was added dropwise over a period of 15 minutes 1.2 g (0.011 mole) of ethyl chloroformate in 10 ml of CHCl3. The mixture was refluxed for 2 hours and was made basic with 0.8 g of sodium hydroxide in 25 ml of water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04656175 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-c440bfb63da54f03ab6fc20d5f589279 |
| Source note | uspto-grants-1987_04 |