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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 542194Generated: November 2, 2026

1-[Bis(hydroxymethyl)-methyl]-6,7-diethoxy-3,4-dihydroisoquinoline → 2-(6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-propane-1,3-diol

https://huagongshe.com/reaction/542194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[Bis(hydroxymethyl)-methyl]-6,7-diethoxy-3,4-dihydroisoquinolineHCID 13696682—
SolventBenzeneHCID 241—
Product2-(6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-propane-1,3-diolHCID 13696683—

Reaction Steps

The 6,7-diethoxy analogue of the above compound can be prepared in an analogous manner, starting from 1-[bis(hydroxymethyl)-methyl]-6,7-diethoxy-3,4-dihydroisoquinoline; melting point: 127° to 128 C.° (benzene).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04656179
Source datasetuspto-grants-1987_04
ORD IDord-ecb2e419a5f74823a25e7827ad07995e
Source noteuspto-grants-1987_04