2-Azidomethylanthraquinone → 2-Aminomethylanthraquinone

HRID 542400노트

반응식

HRID 542400 반응식
[N:1]([CH2:4][C:5]1[CH:18]=[CH:17][C:16]2[C:15](=[O:19])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8](=[O:20])[C:7]=2[CH:6]=1)=[N+]=[N-].[H][H]>CN(C=O)C.[Pt]>[NH2:1][CH2:4][C:5]1[CH:18]=[CH:17][C:16]2[C:15](=[O:19])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8](=[O:20])[C:7]=2[CH:6]=1

참가 물질

5

반응물 2

HCID 200322122-AzidomethylanthraquinoneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 199878022-Aminomethylanthraquinone수율 75.9%

시약·촉매·용매 2

HCID 23939Platinum촉매HCID 6228Dimethylformamide용매

실험 절차

9.5 g of 2-azidomethylanthraquinone are dissolved in 100 ml of DMF, 1.0 g of platinum-on-charcoal catalyst (5% by weight of Pt) is added and hydrogenation is carried out with hydrogen for 15 minutes. The catalyst is filtered off, 200 ml of water are added to the filtrate and the mixture is filtered. The red crystals which have precipitated are recrystallised from dioxane. 6.5 g (70.01% of theory) of 2-aminomethylanthraquinone are obtained; melting point: 170°-78° C.

후처리

  1. filtrationThe catalyst is filtered off
  2. addition200 ml of water are added to the filtrate
  3. filtrationthe mixture is filtered
  4. customThe red crystals which have precipitated
  5. customare recrystallised from dioxane

출처 및 근거

ORD 기록
ord-7f7d9a20e9784cfc81131317a069da7d
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04657842

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