反应详情

温度

5 °C

A mixture of 224 g of reduced iron, 13.4 g of ammonium chloride, 1,000 ml of isopropyl alcohol, and 200 ml of water was prepared, and then 237 g of ethyl p-nitrobenzoylacetate was added thereto in small amounts at temperatures ranging between 50° and 70° C. They were reacted at 70° C. for 1 hour and then the reaction solution was filtered. Then, 1,000 ml of water was added to the filtrate and cooled to 5° C., and crystals precipitated were collected by filtration to yield 172 g of yellow ethyl p-aminobenzoylacetate crystals, m.p., 82°-4° C.

1. customwas prepared
2. customranging between 50° and 70° C
3. customThey were reacted at 70° C. for 1 hour
4. filtrationthe reaction solution was filtered
5. additionThen, 1,000 ml of water was added to the filtrate
6. customcrystals precipitated
7. filtrationwere collected by filtration