反应详情

A solution of 1.5 g (0.03 mol) of hydrazine hydrate in 50 ml of EtOH was treated with 3.86 g (0.02 mol) of 1-adamantyl isothiocyanate, and stirred for one hour at room temperature. The product was collected and washed two times with EtOH, affording 4.33 g (96%) of 4-(1-adamantyl)-3-thiosemicarbazide, mp 206°-207° C. This thiosemicarbazide is disclosed in Chemical Abstracts, 70: 11223 (1969); and in U.S. Pat. No. 3,406,180.

1. customThe product was collected
2. washwashed two times with EtOH