Hydrochloric Acid → HCID 20208485, compound

HRID 542498Notes

Reaction equation

HRID 542498 reaction equation
[ClH:1].[CH:2]([NH:5][C:6]1[O:11][C:10](=[O:12])[C:9]2[C:13]([CH3:17])=[CH:14][CH:15]=[CH:16][C:8]=2[N:7]=1)([CH3:4])[CH3:3].C(OCC)C>O1CCOCC1>[ClH:1].[CH:2]([NH:5][C:6]1[O:11][C:10](=[O:12])[C:9]2[C:13]([CH3:17])=[CH:14][CH:15]=[CH:16][C:8]=2[N:7]=1)([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 98158285-methyl-2-(propan-2-ylamino)-3,1-benzoxazin-4-one

Product 1

HCID 20208485HCID 20208485, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent2×

Procedure

A twofold stoichiometric excess of 3% hydrogen chloride in dioxane is added to a solution of 1.0 g. of 2-isopropylamino-5-methyl-4H-3,1-benzoxazin-4-one in 20 ml dioxane. Diethyl ether is added until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized to give 2-isopropylamino-5-methyl-4H-3,1-benzoxazin-4-one hydrochloride.

Workup

  1. filtrationThe product is filtered
  2. washwashed with ether, air
  3. customdried
  4. customrecrystallized

Sources & evidence

ORD record
ord-62eecbb3292b426eb426b4e54b54a1ba
Source dataset
uspto-grants-1987_04
Patent number
US04657893

Reaction notes

Loading…