HCID 13672378, compound → HCID 178526257, compound

HRID 542546Notes

Reaction equation

HRID 542546 reaction equation
C([O:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N+:12]([O-:19])=[C:11]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][OH:31])[CH:10]=1)C1C=CC=CC=1>CO.[C].[Pd]>[OH:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N+:12]([O-:19])=[C:11]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][OH:31])[CH:10]=1

Participants

4

Reactant 1

HCID 13672378HCID 13672378, compound

Product 1

HCID 178526257HCID 178526257, compoundYield 57.5%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

In this example, 4-benzyloxy-2-(11-hydroxyundecyl) quinoline-N-oxide is dissolved in methanol and catalytically reduced with a catalyst of 10% palladium-carbon under the atmospheric pressure. Then, the catalyst is removed therefrom by filtration, and the solvent is also removed therefrom by distillation. The residue is recrystallized from ethanol, whereby the cationed compound is obtained (yield: 57.5%).

Workup

  1. customThen, the catalyst is removed
  2. filtrationby filtration
  3. customthe solvent is also removed
  4. distillationby distillation
  5. customThe residue is recrystallized from ethanol, whereby the cationed compound
  6. customis obtained (yield: 57.5%)

Sources & evidence

ORD record
ord-e37e2f3136804670a716b2399ca4f50f
Source dataset
uspto-grants-1987_04
Patent number
US04657916

Reaction notes

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