Hydroxyamine hydrochloride → HCID 13732598, compound

Participants

Reaction Steps

1-Ethyl-4-hydroxy-5-(3-methylbenzoyl)-1H-pyrazolo[3,4-b]pyridine (4.25 g) was refluxed overnight in 75 ml of pyridine containing 4.5 g of hydroxylamine hydrochloride. The pyridine was then removed under reduced pressure and the residue triturated with 5% hydrochloric acid. The product was then filtered off and recrystallized from methanol to give 2.63 g of analytically pure product, mp 122°-123° C.

Provenance & Evidence