Hydroxyamine hydrochloride → HCID 13732604, compound

HRID 542562Notes

Reaction equation

HRID 542562 reaction equation
[CH2:1]([N:3]1[C:7]2=[N:8][CH:9]=[C:10]([C:13](=O)[C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)[C:11]([OH:12])=[C:6]2[CH:5]=[N:4]1)[CH3:2].Cl.[NH2:24]O>N1C=CC=CC=1>[CH2:1]([N:3]1[C:7]2=[N:8][CH:9]=[C:10]3[C:13]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=4)=[N:24][O:12][C:11]3=[C:6]2[CH:5]=[N:4]1)[CH3:2]

Participants

4

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 178463026HCID 178463026, compound

Product 1

HCID 13732604HCID 13732604, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

1-Ethyl-4-hydroxy-5-(3-methoxybenzoyl)-1H-pyrazolo-[3,4-b]pyridine was refluxed overnight in 75 ml of pyridine containing 7.0 g of hydroxylamine hydrochloride. The pyridine was evaporated and the residue triturated with 5% hydrochloric acid. The product thus obtained was recrystallized from methanol to give 5.94 g, mp 130°-131° C.

Workup

  1. customThe pyridine was evaporated
  2. customthe residue triturated with 5% hydrochloric acid
  3. customThe product thus obtained
  4. customwas recrystallized from methanol
  5. customto give 5.94 g, mp 130°-131° C.

Sources & evidence

ORD record
ord-16c61c9facce4e9d8e80fc1325fb9b4b
Source dataset
uspto-grants-1987_04
Patent number
US04658029

Reaction notes

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