反应详情

The sulfonamide (2.3 g, 0.007 m) was suspended in 3N hydrochloric acid and heated to reflux for 16 hours. The mixture was concentrated in vacuo and the residue crystallized from methanol to give 8-methoxy-7-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride, m.p. 270°-274°.

1. temperatureheated
2. temperatureto reflux for 16 hours
3. concentrationThe mixture was concentrated in vacuo
4. customthe residue crystallized from methanol