Hydrogen Bromide → HCID 21242944, compound

HRID 542742Notes

Reaction equation

HRID 542742 reaction equation
[Br:1]C1C=C(OC)C2CCN(C)CCC=2C=1.Cl.C[O:18][C:19]1[C:29]2[CH:28]=[CH:27][N:26]([CH3:30])[CH2:25][CH2:24][C:23]=2[CH:22]=[C:21]([S:31]([CH3:34])(=[O:33])=[O:32])[CH:20]=1.Br>>[BrH:1].[OH:18][C:19]1[C:29]2[CH:28]=[CH:27][N:26]([CH3:30])[CH2:25][CH2:24][C:23]=2[CH:22]=[C:21]([S:31]([CH3:34])(=[O:33])=[O:32])[CH:20]=1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 21242939HCID 21242939, compoundHCID 21242962HCID 21242962, compound

Product 1

HCID 21242944HCID 21242944, compound

Procedure

By the same procedure, 8-bromo-6-methoxy-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine is converted to 6-methoxy-3-methyl-8-methylsulfonyl-1H-3-benzazepine hydrochloride which is treated with 48% hydrobromic acid to give 6-hydroxy-3-methyl-8-methylsulfonyl-1H-3benzazepine hydrobromide.

Sources & evidence

ORD record
ord-c46836f50abd41f2843e71f0141bacbf
Source dataset
uspto-grants-1987_04
Patent number
US04659706

Reaction notes

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