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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 542745Generated: October 31, 2026

Sodium Hydroxide → SK&F 103829

https://huagongshe.com/reaction/542745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant8-hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromideHCID 21242877—
ProductSK&F 103829HCID 130981—

Reaction Steps

8-Hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide is treated with one equivalent of sodium hydroxide in aqueous solution. Extracting into chloroform and evaporating gives 8-hydroxy-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04659706
Source datasetuspto-grants-1987_04
ORD IDord-d507a56eecf146f5943541a84d877583
Source noteuspto-grants-1987_04