Dibenzylamine → 1-Chloro-3-dibenzylamino-2-propanol

HRID 542784Notes

Reaction equation

HRID 542784 reaction equation
[CH2:1]([NH:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:16]([CH:18]1[O:20][CH2:19]1)[Cl:17]>>[Cl:17][CH2:16][CH:18]([OH:20])[CH2:19][N:8]([CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 7656DibenzylamineHCID 7835Epichlorohydrin

Product 1

HCID 135354791-Chloro-3-dibenzylamino-2-propanolYield 70%

Procedure

4.93 g (0.25 mol) of dibenzylamine and 25.4 g (0.275 mol) of epichlorohydrin are stirred for 3 hours under nitrogen at 85° to 90° C. The golden yellow oil obtained is distilled under a high vacuum. 50.5 g (70%) of a colourless oil are obtained.

Workup

  1. customThe golden yellow oil obtained
  2. distillationis distilled under a high vacuum

Sources & evidence

ORD record
ord-4efc1c1d1de14a078d90d2ea6b6dbe1c
Source dataset
uspto-grants-1987_04
Patent number
US04659721

Reaction notes

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