HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 1-methyl-3-(1-methyl-1H-tetrazol-5-yl)-7-pyrrolidino-4-quinolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 7-fluoro-1-methyl-3-(1-methyl-1H-tetrazol-5-yl)-4-quinolone | HCID 13474453 | — |
| Product | 1-methyl-3-(1-methyl-1H-tetrazol-5-yl)-7-pyrrolidino-4-quinolone | HCID 13474432 | — |
Reaction Steps
In a similar way to that described in Example 30, 7-fluoro-1-methyl-3-(1-methyl-1H-tetrazol-5-yl)-4-quinolone (5 g) was boiled under reflux with pyrrolidine (50 ml) for 20 hours to give 1-methyl-3-(1-methyl-1H-tetrazol-5-yl)-7-pyrrolidino-4-quinolone, m.p. 267°-270° (from industrial methylated spirit:water 5:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04659718 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-31e07a661a0e474dafa0cd89e6078070 |
| Source note | uspto-grants-1987_04 |