Ethanol → HCID 20205717, compound

HRID 543111Notes

Reaction equation

HRID 543111 reaction equation
[P:1]([O-:8])([O:5]CC)[O:2]CC.O.[CH2:10](O)[CH3:11].[CH:13]1([NH2:18])[CH2:17][CH2:16][CH2:15][CH2:14]1>CO>[CH2:10]([P:1](=[O:2])([O-:5])[O-:8])[CH3:11].[CH:13]1([NH3+:18])[CH2:17][CH2:16][CH2:15][CH2:14]1.[CH:13]1([NH3+:18])[CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

6

Reactant 4

HCID 702EthanolHCID 962WaterHCID 2906CyclopentylamineHCID 3780918Diethylphosphite

Product 1

HCID 20205717HCID 20205717, compoundYield 91.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 13.81 g. (0.1 moles) of diethyl phosphite, 20 ml. of water and 20 ml. of ethanol is reacted with a mixture of 8.51 g. (0.1 moles) of cyclopentyl amine and 30 ml. of methanol as described in Example 1. 17.9 g. of cyclopentyl-ammoniumethyl phosphonate are obtained. nD30 -1.4622. Yield: 91.7%.

Workup

  1. additionA mixture of 13.81 g

Sources & evidence

ORD record
ord-979d3eefb4ff494dbc3f9673d99bf7fe
Source dataset
uspto-grants-1987_04
Patent number
US04661477

Reaction notes

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