反应详情

A mixture of 2.77 g of 4-(3,5-dichloro-4-methylphenyl)-3-hydroxy-4-oxobutyric acid (prepared as described in Preparation 1), 0.5 g of hydrazine hydrate (100%) and 20 ml of ethanol was stirred at room temperature for 6 hours. The resulting white powder was then collected by filtration, to give 1.77 g (yield 65%) of the desired Compound No. 7, melting at 253°-256° C.

1. filtrationThe resulting white powder was then collected by filtration