2',4'-Dihydroxyacetophenone → HCID 21294069, compound

HRID 543227Notes

Reaction equation

HRID 543227 reaction equation
Br[CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8].[CH3:14][C:15]([C:17]1[CH:18]=[CH:19][C:20]([OH:24])=[CH:21][C:22]=1[OH:23])=[O:16]>C(C(C)=O)C>[C:15]([C:17]1[CH:18]=[CH:19][C:20]([O:24][CH:2]([CH2:11][CH2:12][CH3:13])[CH2:3][CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[CH:21][C:22]=1[OH:23])(=[O:16])[CH3:14]

Participants

4

Reactant 2

HCID 69902',4'-DihydroxyacetophenoneHCID 21294048HCID 21294048, compound

Product 1

HCID 21294069HCID 21294069, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

Following the procedure of Example 48, 1.13 g. of methyl 6-bromo-nonanoate and 1.31 g. of 2,4-dihydroxyacetophenone were reacted in 50 ml. of methyl ethyl ketone. Hydrolysis of the resulting methyl ester intermediate gave 0.3 g. of the title product, M+ =308; NMR, IR.

Workup

  1. customgave 0.3 g

Sources & evidence

ORD record
ord-a31493ddec4144528b8cda4c56446404
Source dataset
uspto-grants-1987_04
Patent number
US04661505

Reaction notes

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