HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 3,3-Bisfluoromethyl-1-bromo-butan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-Fluoro-3-(fluoromethyl)-3-methylbutan-2-one | HCID 13019433 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3,3-Bisfluoromethyl-1-bromo-butan-2-one | HCID 13019434 | — |
Reaction Steps
51 ml (1 mol) of bromine were added dropwise to 136 g (1 mol) of 3,3-bisfluoromethylbutane-2-one in 700 ml of methylene chloride such that decoloration was continuous. The solvent was then distilled off under a water pump vacuum. An almost quantitative yield of crude 3,3-bisfluoromethyl-1-bromo-butan-2-one was obtained as an oil, which could be further reacted directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04661640 |
| Source dataset | uspto-grants-1987_04 |
| ORD ID | ord-f771d13f0090404cafd1ea390e83f465 |
| Source note | uspto-grants-1987_04 |