Hexamethylenetetramine → HCID 13423723, compound

HRID 543378Notes

Reaction equation

Cl.N[CH2:3][C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH2:17][CH3:18])(=[O:16])=[O:15])[C:5]=1[OH:19].C1N2CN3CN(C2)CN1C3.FC(F)(F)C(O)=[O:33]>>[CH:3]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH2:17][CH3:18])(=[O:16])=[O:15])[C:5]=1[OH:19])=[O:33]

Participants

Reactant 3

HCID 4101Hexamethylenetetramine

HCID 6422Trifluoroacetic acid

HCID 13210272HCID 13210272, compound

Product 1

HCID 13423723HCID 13423723, compound

Procedure

0.615 g of 2-aminomethyl-4-(1,1-dimethylethyl)-6-ethylsulfonylphenol hydrochloride are reacted with 0.36 g of urotropine in 8 ml of trifluoroacetic acid to give 2-formyl-4-(1,1-dimethylethyl)-6-ethylsulfonylphenol in analogy to Example 1.

Sources & evidence

ORD record: ord-f5dca639e2284059a172f06b839806c6
Source dataset: uspto-grants-1987_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04661636

Reaction notes

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