HRID543530

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5462222

Potassium

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(N)=O)CS[C@H]12)c1ccco1$

HCID5479529

Cefuroxime

C16H16N4O8S

HCID20461839

Bromomethyl 3-methylbutanoate

C6H11BrO2

PRODUCTS

生成物

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)OCOC(=O)CC(C)C)=C(COC(N)=O)CS[C@H]12)c1ccco1$

HCID177714162

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Bromomethyl 3-methylbutanoate (1.328 g, 6.7 mmole) was added to a solution of (6R,7R)-3-carbamoyloxymethyl-7-[(Z)-2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylic acid, potassium salt (2.772 g, 6 mmole) in purified N,N dimethylformamide (18 ml). The mixture was allowed to react for 15 minutes and was then worked up as described in Example 4 to give the slightly impure title compound (2.809 g).

WORKUP

后处理

customto react for 15 minutes