Piperidine → HCID 22826496, compound

HRID 543653Notes

Reaction equation

HRID 543653 reaction equation
C([O:4][C@H:5]1[CH:10]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[CH2:9][C@H:8]2[C@H:17]3[C@H:27]([CH2:28][CH2:29][C@:6]12[CH3:7])[C@:25]1([CH3:26])[C@H:20]([CH2:21][C@@H:22]([CH3:31])[C:23](=O)[CH2:24]1)[CH2:19][CH2:18]3)(=O)C.[NH:32]1[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]1>C(O)=O>[CH3:31][C@H:22]1[C@@H:23]([N:32]2[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33]2)[CH2:24][C@@:25]2([CH3:26])[C@@H:20]([CH2:19][CH2:18][C@@H:17]3[C@@H:27]2[CH2:28][CH2:29][C@@:6]2([CH3:7])[C@H:8]3[CH2:9][C@H:10]([N:11]3[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]3)[C@@H:5]2[OH:4])[CH2:21]1

Participants

4

Reactant 2

HCID 8082PiperidineHCID 70501715HCID 70501715, compound

Product 1

HCID 22826496HCID 22826496, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

17β-Acetyloxy-3β-methyl-16-(1-piperidinyl)-5α-androstan-2-one was treated with piperidine and formic acid, as described in Example I(h), to give 3β-methyl-2β,16β-di-(1-piperidinyl)-5α-androstan-17β-ol.

Sources & evidence

ORD record
ord-526169d9793c410992a96e9b0c01f80d
Source dataset
uspto-grants-1984_05
Patent number
US04447425

Reaction notes

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