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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 543682Generated: October 30, 2026

Formaldehyde → HCID 178487896, compound

https://huagongshe.com/reaction/543682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantHCID 178487890HCID 178487890—
SolventSodium HydroxideHCID 14798—
ProductHCID 178487896HCID 178487896—

Reaction Steps

4-Hydroxy-6-methoxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide (initially at 40°-50°, then kept at 60° for 18 hours) to give the novel compound 4-hydroxy-3-hydroxymethyl-6-methoxyquinoline, m.p. 327°-334°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04447435
Source datasetuspto-grants-1984_05
ORD IDord-403c408712b7453687c262c06be1dffe
Source noteuspto-grants-1984_05