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HRID543685

反应详情

EQUATION

反应方程式

HRID 543685 的结构方程式

REACTANTS

反应物

3
结构：C=O
HCID712

Formaldehyde

CH2O

结构：ClCCl
HCID6344

Dichloromethane

CH2Cl2

结构：Oc1ccnc2c(F)cccc12
HCID178516458

未命名化合物

PRODUCTS

生成物

1
结构：OCc1cnc2c(F)cccc2c1O
HCID178519817

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Na+].[OH-]
溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

8-Fluoro-4-hydroxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 8-fluoro-4-hydroxy-3-hydroxymethylquinoline, m.p. 176°-178° (from dichloromethane).