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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 543685Generated: October 30, 2026

Formaldehyde → HCID 178519817, compound

https://huagongshe.com/reaction/543685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantDichloromethaneHCID 6344—
ReactantHCID 178516458HCID 178516458—
SolventSodium HydroxideHCID 14798—
ProductHCID 178519817HCID 178519817—

Reaction Steps

8-Fluoro-4-hydroxyquinoline was reacted with formaldehyde in aqueous sodium hydroxide to give the novel compound 8-fluoro-4-hydroxy-3-hydroxymethylquinoline, m.p. 176°-178° (from dichloromethane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04447435
Source datasetuspto-grants-1984_05
ORD IDord-4faeb6a49c4e460c88aeba2201e6eccf
Source noteuspto-grants-1984_05