Methyl iodide → HCID 13247791, compound

Participants

Reaction Steps

A mixture of 1-methyl-4-piperidyl 2-piperidino-2-(1,2-benzisoxazol-3-yl)acetate (1 g), methyl iodide (2.5 g), and acetone (10 ml) was allowed to stand at room temperature for 5 hours. The resulting crystals were recrystallized from ethanol-methanol to give 1,1-dimethyl-4-[2-piperidino-2-(1,2-benzisoxazol-3-yl)acetoxy]piperidinium iodide (1.1 g), m.p. 176°-178° C.

Provenance & Evidence