Hydrochloric Acid → HCID 20460474, compound

Participants

Reaction Steps

93 g (0.55 mol) of bromoacetyl chloride were added dropwise, with stirring, to a suspension of 105 g (0.5 mol) of 5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one in 1 liter of toluene, at 90° C. The mixture was then refluxed for a further 30 minutes, during which there was a strong development of hydrogen chloride. After cooling, the dark blue crystal slurry obtained was suction filtered;

Provenance & Evidence