Ammonia → HCID 70478162, compound

Participants

Reaction Steps

A mixture of 4-[2-(1-imidazolylmethyl)-4-methyl-phenoxy]butyric acid ethyl ester (1.0 g) and 0.880 ammonia solution was stirred for 6 hours and allowed to stand for a further 36 hours. The solid was filtered off and crystallised from water to give 4-[2-(1-imidazolylmethyl)-4-methyl-phenoxy]butyramide (0.30 g), m.p. 114°-116° C. Found: C, 65.31, H, 7.23, N, 15.13. C15H19N3O2 requires: C, 65.91, H, 7.01, N, 15.37%.

Provenance & Evidence