Hydrochloric Acid → HCID 70478180, compound

HRID 544118Notes

Reaction equation

HRID 544118 reaction equation
C([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][C:14]2[NH:15][CH:16]=[CH:17][N:18]=2)[CH:8]=1)C.[ClH:20]>C(#N)C>[ClH:20].[NH:15]1[CH:16]=[CH:17][N:18]=[C:14]1[CH2:13][C:9]1[CH:8]=[C:7]([CH:12]=[CH:11][CH:10]=1)[O:6][CH2:5][C:4]([OH:19])=[O:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54015307HCID 54015307, compound

Product 1

HCID 70478180HCID 70478180, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Hydrolysis of 3-(1-imidazolylmethyl)phenoxyacetic acid ethyl ester free base with concentrated hydrochloric acid according to the method of Example 7 gave 3-(1-imidazolylmethyl)phenoxyacetic acid hydrochloride, m.p. 179°-181° C. (from aqueous acetonitrile). Found: C, 52.23, H, 4.84, N, 10.65. C12H12N2O3.HCl requires: C, 53.64, H, 4.88, N, 10.43%.

Sources & evidence

ORD record
ord-70d55c8885474793a020a01aff58d46a
Source dataset
uspto-grants-1984_05
Patent number
US04448781

Reaction notes

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