HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 5-(Chloromethyl)-3-methoxy-1,2-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Methoxy-5-isoxazolemethanol | HCID 10678258 | — |
| Product | 5-(Chloromethyl)-3-methoxy-1,2-oxazole | HCID 10080543 | 87.5% |
Reaction Steps
A mixture of 1.0 g 5-hydroxymethyl-3-methoxy-isoxazole and 10 g thionyl chloride was stirred at room temperature for 20 h. The excess thionylchloride was removed in vacuo, dissolved in toluene and the solvent evaporated. 1.0 g of an oil was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05622953 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-6871ca3f494c4a59b5a335d37e90a551 |
| Source note | uspto-grants-1997_04 |