反应详情

A mixture of N-ethoxycarbonylcyanoacetamide (42 g), triethylorthoformate (40 g) and acetic anhydride (100 ml) is heated at reflux for one hour. The reaction is allowed to stand until cool and then is filtered, washing with ether, to yield α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide.

1. temperatureis heated
2. temperatureat reflux for one hour
3. temperatureuntil cool
4. filtrationis filtered
5. washwashing with ether