HCID 13326257, compound → HCID 13326258, compound

HRID 544203Notes

Reaction equation

HRID 544203 reaction equation
[C:1]([C:6]1[C:7](=[O:23])[NH:8][C:9](=[O:22])[N:10]([NH:12][C:13]2[C:18]([Cl:19])=[CH:17][C:16]([Cl:20])=[CH:15][C:14]=2[Cl:21])[CH:11]=1)([O:3]CC)=[O:2]>Cl.C(O)(=O)C>[C:1]([C:6]1[C:7](=[O:23])[NH:8][C:9](=[O:22])[N:10]([NH:12][C:13]2[C:14]([Cl:21])=[CH:15][C:16]([Cl:20])=[CH:17][C:18]=2[Cl:19])[CH:11]=1)([OH:3])=[O:2]

Participants

4

Reactant 1

HCID 13326257HCID 13326257, compound

Product 1

HCID 13326258HCID 13326258, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 313Hydrochloric AcidSolvent

Procedure

5-Carbethoxy-1-(2,4,6-trichloroanilino)-2,4-pyrimidinedione is dissolved in a hot mixture of concentrated HCl and glacial acetic acid (1:1) and is refluxed for 10 hours. The reaction mixture is cooled to RT and filtered, giving 5-carboxy-1-(2,4,6-trichloroanilino)-2,4-pyrimidinedione.

Workup

  1. temperatureis refluxed for 10 hours
  2. filtrationfiltered

Sources & evidence

ORD record
ord-d4349b9e02994f469a7ded0cc9656cb9
Source dataset
uspto-grants-1984_05
Patent number
US04448961

Reaction notes

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