N-bromobutanimide → HCID 13326260, compound

HRID 544204Notes

Reaction equation

HRID 544204 reaction equation
[Br:1]N1C(=O)CCC1=O.[Cl:9][C:10]1[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([Cl:26])[C:11]=1[NH:12][N:13]1[CH:18]=[CH:17][C:16](=[O:19])[NH:15][C:14]1=[O:20]>C(O)(=O)C>[Br:1][C:17]1[C:16](=[O:19])[NH:15][C:14](=[O:20])[N:13]([NH:12][C:11]2[C:21]([Cl:26])=[CH:22][C:23]([Cl:25])=[CH:24][C:10]=2[Cl:9])[CH:18]=1

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 13326259HCID 13326259, compound

Product 1

HCID 13326260HCID 13326260, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

An excess of N-bromosuccinimide in acetic acid is added to 1-(2,4,6-trichloroanilino)-2,4-pyrimidinedione and the mixture is refluxed for 10 hours. It is cooled to RT and is then poured into ice and filtered to give 5-bromo-1-(2,4,6-trichloroanilino)-2,4-pyrimidinedione.

Workup

  1. temperaturethe mixture is refluxed for 10 hours
  2. additionis then poured into ice
  3. filtrationfiltered

Sources & evidence

ORD record
ord-ba80c9f26a574143b84fd07f58ecaab7
Source dataset
uspto-grants-1984_05
Patent number
US04448961

Reaction notes

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