反应详情

In this reference example, 15.01 g of 1-benzyl-3-piperidine methanol and 6.76 g of diketene were reacted similarly as in Reference Example 1, and the reaction product was purified by silica gel column chromatography (eluent:n-hexane:ethyl acetate=1:1 v/v), to obtain 17.50 g of acetoacetic acid-(N-benzyl-3-piperidinylmethyl) ester (yield: 82.5%).

1. customthe reaction product was purified by silica gel column chromatography (eluent:n-hexane:ethyl acetate=1:1 v/v)