HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- → HCID 52609464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)- | HCID 85083 | — |
| Reactant | N-Methyl-3-phenylpropan-1-aMine hydrochloride (RelCpd B) | HCID 9549628 | — |
| Product | HCID 52609464 | HCID 52609464 | — |
Reaction Steps
By the method of part A of Example 1 N-(tert-butyloxycarbonyl)-L-proline (4.3 g.) was condensed with N-methyl-3-phenylpropylamine hydrochloride (3.71 g.) and the product was purified by high pressure liquid chromatography on silica gel using hexane-ethyl acetate (3:2) as the eluant, affording 1-(tert-butyloxycarbonyl)-N-methyl-N-(3-phenylpropyl)-L-prolinamide as a syrup (2.65 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04450155 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-145c3c6ea96c436f990872ed42b9978d |
| Source note | uspto-grants-1984_05 |