HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Baxitozine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Hydroxy-4-oxo-4-(3,4,5-trimethoxyphenyl)butanoic acid | HCID 3069179 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Baxitozine | HCID 6366494 | — |
Reaction Steps
15.8 g of 4-(3,4,5-trimethoxyphenyl)-4-oxo-2-hydroxy butanoic acid obtainedin Example 3, 20 cc of acetic acid and 20 cc of concentrated hydrochloric acid (d-1.18) are heated for 2.5 hours under reflux.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04450292 |
| Source dataset | uspto-grants-1984_05 |
| ORD ID | ord-f53a38bf7b244fc5a65abee937ff5daf |
| Source note | uspto-grants-1984_05 |