Ammonia → HCID 20458236, compound

Participants

Reaction Steps

This thiourea was stirred for 18 hours with yellow mercuric oxide (10 g.) in methanolic ammonia (250 ml.). The mixture was filtered, the filtrate was evaporated to dryness and the residue was extracted with hot CH2Cl2. Evaporation of the CH2Cl2 solution gave 2-(3-benzyloxypropyl)-4-[2-(2,2,2-trifluoroethyl)guanidino]pyrimidine (9.2 g.) which was used without further purification.

Provenance & Evidence