HCID 20202846, compound → HCID 20458260, compound

HRID 544581Notes

Reaction equation

HRID 544581 reaction equation
[NH2:1][C:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10](OC)=[O:11])[N:3]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>CCOCC>[NH2:1][C:2]1[CH:6]=[N:5][N:4]([C:7]2[CH:16]=[CH:15][CH:14]=[C:9]([CH2:10][OH:11])[CH:8]=2)[N:3]=1

Participants

4

Reactant 2

HCID 20202846HCID 20202846, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20458260HCID 20458260, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A stirred mixture of methyl 3-(4-amino-1,2,3-triazol-2-yl)benzoate (0.312 g.), lithium aluminium hydride (0.10 g.) and ether (50 ml.) was kept at room temperature for 1 hour. The excess of lithium aluminium hydride was destroyed with aqueous NaOH and the mixture was filtered. The filtrate was evaporated to give unpurified 4-amino-2-(3-hydroxymethylphenyl)-1,2,3-triazole.

Workup

  1. customThe excess of lithium aluminium hydride was destroyed with aqueous NaOH
  2. filtrationthe mixture was filtered
  3. customThe filtrate was evaporated

Sources & evidence

ORD record
ord-afec93e93eab4688962a0ec4d7acdda7
Source dataset
uspto-grants-1984_05
Patent number
US04451463

Reaction notes

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