4-Chlorobenzoyl chloride → HCID 20458410, compound

HRID 544589Notes

Reaction equation

HRID 544589 reaction equation
[CH2:1]([N:3]1[CH2:10][CH:9]2[CH:11]([OH:12])[CH:5]([CH2:6][N:7]([CH2:13][CH3:14])[CH2:8]2)[CH2:4]1)[CH3:2].[Cl:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](Cl)=[O:21])=[CH:18][CH:17]=1>>[OH2:12].[ClH:15].[ClH:15].[CH2:13]([N:7]1[CH2:6][CH:5]2[CH:11]([O:12][C:20](=[O:21])[C:19]3[CH:23]=[CH:24][C:16]([Cl:15])=[CH:17][CH:18]=3)[CH:9]([CH2:10][N:3]([CH2:1][CH3:2])[CH2:4]2)[CH2:8]1)[CH3:14]

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 20458403HCID 20458403, compound

Product 1

HCID 20458410HCID 20458410, compoundYield 53.8%

Procedure

9.9 g of 3,7-diethyl-3,7-diazabicyclo[3.3.1]nonane-9-ol are reacted with 4-chloro-benzoyl chloride as described in Example 8 to obtain 3,7-diethyl-9-(4'-chloro-benzoyloxy)-3,7-diazabicyclo[3.3.1]nonane dihydrochloride monohydrate with a yield of 53.8%; m.p.: 116°-120° C.

Sources & evidence

ORD record
ord-a8512eaefd344afcb07ff8f963393b83
Source dataset
uspto-grants-1984_05
Patent number
US04451473

Reaction notes

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