4-Chlorophenol → 1-[(6-Bromohexyl)oxy]-4-chlorobenzene

HRID 544609Notes

Reaction equation

[K].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[Br:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]Br>>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][Br:10])=[CH:5][CH:4]=1

Participants

Reactant 3

HCID 46844-Chlorophenol

HCID 123681,6-Dibromohexane

HCID 5462222Potassium

Product 1

HCID 114492081-[(6-Bromohexyl)oxy]-4-chlorobenzene

Procedure

The intermediate 6-(4-chlorophenoxy)hexyl bromide was prepared from the potassium salt of 4-chlorophenol and 1,6-dibromohexane.

Sources & evidence

ORD record: ord-cc8d10957ff24806b7c9c6b37971fd11
Source dataset: uspto-grants-1984_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04451476

Reaction notes

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