Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methyl-3-nitroanisole → 5-Methoxy-o-toluidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methyl-3-nitroanisole | HCID 87137 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-Methoxy-o-toluidine | HCID 99500 | — |
반응 단계
12.4 g of palladium-on-carbon are added to a solution of 132.9 g (0.759 mole) of 4-methyl-3-nitro-anisole in 1.1 liters of methanol and hydrogenation is carried out at room temperature. The catalyst is filtered off and the filtrate is concentrated in a vacuum rotary evaporator. Recrystallisation from isopropanol/water yields 3-amino-4-methylanisole having a melting point of 43°-44°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04451462 |
| 출처 데이터셋 | uspto-grants-1984_05 |
| ORD ID | ord-6c3bae7188a248158e890e52b408fc42 |
| 출처 메모 | uspto-grants-1984_05 |