p-Fluoronitrobenzene → Nitrobenzene
Reaction equation
[OH-].[Na+].F[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=1>O.[Cl-].C([N+](CC)(CC)CC)C1C=CC=CC=1>[N+:10]([C:7]1[CH:8]=[CH:9][CH:4]=[CH:5][CH:6]=1)([O-:12])=[O:11]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 60 °C
Procedure
A solution of sodium hydroxide (7.1 g) in water (7.1 g) and benzyltriethylammonium chloride (0.4 g) was added to a mixture of 4-fluoronitrobenzene (14.1 g) and 1,1,7-trihydryl-F-heptanol (36 g). The whole was stirred and heated at about 60° C. for about 6 hours. The product was recrystallized from an ethanol/petroleum ether mixture to give 4-(1,1,7-trihydryl-F-hepyloxy) nitrobenzene (37.2 g), having a melting point of 51°-53° C.
Workup
- customThe product was recrystallized from an ethanol/petroleum ether mixture
Sources & evidence
- ORD record
- ord-9c5109867c2d436daa71fdf51c714d05
- Source dataset
- uspto-grants-1984_05
- Patent number
- US04451645
Reaction notes
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