HRID544777

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID84431

5,6-Dimethoxyindole

C10H11NO2

HCID170432

1H-Indole, 1-ethyl-2-methyl-

C11H13N

结构：CCn1c(C)c(C2=CC(c3c(C)n(CC)c4ccccc34)C(=O)O2)c2ccccc21

HCID20442724

3,5-Bis(1-ethyl-2-methyl-1H-indol-3-yl)furan-2(3H)-one

C26H26N2O2

结构：O=C1OC(c2cn(Cc3ccccc3)c3cc(F)ccc23)=CC1c1cn(Cc2ccccc2)c2cc(F)ccc12

HCID20442790

未命名化合物

PRODUCTS

生成物

结构：COc1cc2[nH]cc(C3(c4cn(Cc5ccccc5)c5cc(F)ccc45)C=C(c4cn(Cc5ccccc5)c5cc(F)ccc45)C(=O)O3)c2cc1OC

HCID20442760

未命名化合物

PROCEDURE

实验过程

When 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-2(3H)-furanone is substituted for 3,5-bis(1-ethyl-2-methyl-3-indolyl)-2(3H)-furanone and 5,6-dimethoxyindole is substituted for 1-ethyl-2-methylindole in the procedure described in part C of this example, there is obtained 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-5-(5,6-dimethoxy-3-indolyl)-2(5H)-furanone (Formula III: R=C6H5CH2 ; R1 =R2 =R3 =H; Y=6-F; Y1 =5,6-(CH3O)2).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cd52910be2d2430e942687524cf0cb24
来源数据集: uspto-grants-1984_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04451657
来源说明: uspto-grants-1984_05

反应 SMILES

[F:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH:18]3[CH:22]=[C:21]([C:23]4[C:31]5[C:26](=[CH:27][C:28]([F:32])=[CH:29][CH:30]=5)[N:25]([CH2:33][C:34]5[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=5)[CH:24]=4)[O:20][C:19]3=[O:40])=[CH:7][N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.C(N1C2C(=CC=CC=2)C(C2C=C(C3C4C(=CC=CC=4)N(CC)C=3C)OC2=O)=C1C)C.[CH3:71][O:72][C:73]1[CH:74]=[C:75]2[C:79](=[CH:80][C:81]=1[O:82][CH3:83])[NH:78][CH:77]=[CH:76]2.C(N1C2C(=CC=CC=2)C=C1C)C>>[F:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:18]3[C:19](=[O:40])[O:20][C:21]([C:23]4[C:31]5[C:26](=[CH:27][C:28]([F:32])=[CH:29][CH:30]=5)[N:25]([CH2:33][C:34]5[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=5)[CH:24]=4)([C:76]4[C:75]5[C:79](=[CH:80][C:81]([O:82][CH3:83])=[C:73]([O:72][CH3:71])[CH:74]=5)[NH:78][CH:77]=4)[CH:22]=3)=[CH:7][N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:4][CH:3]=1