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5,6-Dimethoxyindole → 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-5-(5,6-dimethoxy-3-indolyl)-2(5H)-furanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5,6-Dimethoxyindole | HCID 84431 | — |
| 反応物 | 1H-Indole, 1-ethyl-2-methyl- | HCID 170432 | — |
| 反応物 | 3,5-Bis(1-ethyl-2-methyl-1H-indol-3-yl)furan-2(3H)-one | HCID 20442724 | — |
| 反応物 | 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-2(3H)-furanone | HCID 20442790 | — |
| 生成物 | 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-5-(5,6-dimethoxy-3-indolyl)-2(5H)-furanone | HCID 20442760 | — |
反応手順
When 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-2(3H)-furanone is substituted for 3,5-bis(1-ethyl-2-methyl-3-indolyl)-2(3H)-furanone and 5,6-dimethoxyindole is substituted for 1-ethyl-2-methylindole in the procedure described in part C of this example, there is obtained 3,5-bis(6-fluoro-1-benzyl-3-indolyl)-5-(5,6-dimethoxy-3-indolyl)-2(5H)-furanone (Formula III: R=C6H5CH2 ; R1 =R2 =R3 =H; Y=6-F; Y1 =5,6-(CH3O)2).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04451657 |
| 出典データセット | uspto-grants-1984_05 |
| ORD ID | ord-cd52910be2d2430e942687524cf0cb24 |
| 出典メモ | uspto-grants-1984_05 |